Acute and chronic cycle length dependent increase in ventricular pacing threshold
| Autor: | David J. Callans, Belinda T. Flores, Francis E. Marchlinski, Robert B. Kleiman, Richard L. Perlman, Bruce G. Hook, Michael S. Hanna |
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| Rok vydání: | 1992 |
| Předmět: |
Male
medicine.medical_specialty Pacemaker Artificial Time Factors medicine.medical_treatment Internal medicine medicine Hospital discharge Humans Lead (electronics) Cycle length Epicardial lead business.industry Cardiac Pacing Artificial General Medicine Equipment Design Ventricular pacing Middle Aged Implantable cardioverter-defibrillator Surgery Defibrillators Implantable Electrodes Implanted Outpatient visits Cardiology Tachycardia Ventricular Female Cardiology and Cardiovascular Medicine business Cadence Anti-Arrhythmia Agents Follow-Up Studies |
| Zdroj: | Pacing and clinical electrophysiology : PACE. 15(10 Pt 1) |
| ISSN: | 0147-8389 |
| Popis: | Several factors have been shown to influence ventricular pacing threshold in humans, including pacing lead location (endocardial vs epicardial), lead maturation, and antiarrhythmic agents. To determine whether ventricular pacing rate has a significant influence on acute and chronic pacing thresholds, we measured pacing thresholds in 16 patients receiving an implantable antitachycardia pacemaker cardioverter defibrillator (Cadence). Ventricular pacing thresholds were determined using the device programmer at cycle lengths of 600, 400 and 300 msec at the time of implantation; prior to hospital discharge at 3-14 days; and during follow-up outpatient visits at 6-8 weeks, 3 months, and 6 months to 1 year. Eleven patients had an epicardial lead system and five an endocardial lead system. Eleven patients were being treated with antiarrhythmic drug therapy. Device output ranged from 1-10 V and was adjustable in 1-V increments (pulse width was held constant at 1 msec). A cycle length dependent increase in pacing threshold (defined as a > or = 1-V increase in threshold at 400 or 300 msec relative to 600 msec) was observed in 10/16 patients during 12/72 pacing trials at 400 msec, and in 15/16 patients during 31/67 trials at 300 msec. In trials in which an increase in pacing threshold occurred, the magnitude of the increase at 400 msec relative to 600 msec was only 1 V in all 12 trials, but at 300 msec the increase ranged from 4-9 V in 7/31 (23%) trials.(ABSTRACT TRUNCATED AT 250 WORDS) |
| Databáze: | OpenAIRE |
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