Absence of ototoxicity of teichomycin A2 in guinea pigs
| Autor: | R E Brummett, D Himes, K E Fox, M Warchol |
|---|---|
| Rok vydání: | 1987 |
| Předmět: |
medicine.drug_class
medicine.medical_treatment Antibiotics Guinea Pigs Perilymph Pharmacology Guinea pig Ototoxicity Reflex medicine Animals Pharmacology (medical) Ear Diseases Teicoplanin business.industry Teichomycin A2 Glycopeptides Drug Synergism medicine.disease Cochlea Infectious Diseases Ethacrynic Acid Anesthesia Toxicity Vancomycin Diuretic business medicine.drug Research Article |
| Zdroj: | Antimicrobial agents and chemotherapy. 31(4) |
| ISSN: | 0066-4804 |
| Popis: | Teichomycin A2 is a new antibiotic that is similar to vancomycin. Because vancomycin is reported to be ototoxic, teichomycin A2 was tested for ototoxicity. No evidence of ototoxicity was found. Furthermore, ethacrynic acid, a diuretic that augments the ototoxicity of many drugs, did not enhance ototoxicity with teichomycin A2. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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