Bone Marrow Aspirate Clot: A Useful Technique in Diagnosis and Follow-Up of Hematological Disorders

Autor: Ligia Niero-Melo, Rafael Dezen Gaiolla, Cristiano Claudino Oliveira, Lucas Oliveira Cantadori
Přispěvatelé: Universidade Estadual Paulista (Unesp), Sao Luiz Dor Hosp
Rok vydání: 2019
Předmět:
Zdroj: Case Reports in Hematology, Vol 2019 (2019)
Case Reports in Hematology
Web of Science
Repositório Institucional da UNESP
Universidade Estadual Paulista (UNESP)
instacron:UNESP
ISSN: 2090-6579
2090-6560
DOI: 10.1155/2019/7590948
Popis: Made available in DSpace on 2019-10-04T12:36:31Z (GMT). No. of bitstreams: 0 Previous issue date: 2019-01-01 Bone marrow biopsy is a diagnostic tool largely used in the evaluation of a broad number of disorders that could affect the hematopoietic system. Differently, bone marrow aspirate clot technique is rarely performed even though it has been described in literature. Here, we highlight the utility of the bone marrow aspirate clot, exemplifying through the discussion of three clinical cases in which this technique was used for diagnosis and follow-up purposes: megaloblastic hemopathy, multiple myeloma, and chronic lymphocytic leukemia. Bone marrow clot analysis increases sensitivity to diagnose hemopathies and offers the possibility of morphological evaluation and anatomopathological study, with the advantage of not needing decalcification processes, hence improving antigenic expression in immunohistochemical and FISH techniques. It is an easy-to-perform technique, offering a quick, reliable, and more comfortable procedure for patients. Sao Paulo State Univ UNESP, Med Sch Botucatu, Dept Internal Med, Botucatu, SP, Brazil Sao Paulo State Univ UNESP, Med Sch Botucatu, Dept Pathol, Botucatu, SP, Brazil Sao Luiz Dor Hosp, Dept Pathol, Sao Paulo, SP, Brazil Sao Paulo State Univ UNESP, Med Sch Botucatu, Dept Internal Med, Botucatu, SP, Brazil Sao Paulo State Univ UNESP, Med Sch Botucatu, Dept Pathol, Botucatu, SP, Brazil
Databáze: OpenAIRE
Externí odkaz:
Nepřihlášeným uživatelům se plný text nezobrazuje