A Guide to COVID-19: a global pandemic caused by the novel coronavirus SARS-CoV-2

Autor: Robert D. P. McCarthy, Hannah E. Stepp, Cassandra L. Atzrodt, Insha Maknojia, Kenny T. L. Ta, Jonathan Po, Tiara M. Oldfield, Thomas P. Clements
Rok vydání: 2020
Předmět:
0301 basic medicine
viruses
ACE2
remdesivir
Disease
medicine.disease_cause
Severe Acute Respiratory Syndrome
Biochemistry
Severity of Illness Index
Lopinavir
SARS‐CoV‐2
chloroquine
0302 clinical medicine
COVID-19 Testing
vaccine
Epidemiology
Pandemic
skin and connective tissue diseases
Coronavirus
Alanine
Transmission (medicine)
virus diseases
Drug Combinations
Severe acute respiratory syndrome-related coronavirus
030220 oncology & carcinogenesis
CRISPR
Middle East Respiratory Syndrome Coronavirus
Coronavirus Infections
RT‐qPCR
Interferon beta-1a
medicine.medical_specialty
COVID-19 Vaccines
hydroxychloroquine
Coronavirus disease 2019 (COVID-19)
Antiviral Agents
Virus
MERS‐CoV
03 medical and health sciences
A Guide To…
COVID‐19
MERS
medicine
Humans
Molecular Biology
Pandemics
SARS
Ritonavir
business.industry
SARS-CoV-2
fungi
COVID-19
SARS‐CoV
Cell Biology
medicine.disease
Virology
Respiration
Artificial
Adenosine Monophosphate
COVID-19 Drug Treatment
body regions
Pneumonia
030104 developmental biology
business
Zdroj: The Febs Journal
The FEBS Journal
ISSN: 1742-4658
Popis: The emergence of the SARS-CoV-2 strain of the human coronavirus has thrown the world into the midst of a new pandemic. In the human body, the virus causes COVID-19, a disease characterized by shortness of breath, fever, and pneumonia, which can be fatal in vulnerable individuals. SARS-CoV-2 has characteristics of past human coronaviruses, with close genomic similarities to SARS-CoV, the virus that causes the disease SARS. Like these related coronaviruses, SARS-CoV-2 is transmitted through the inhalation of droplets and interaction with contaminated surfaces. Across the world, laboratories are developing candidate vaccines for the virus - with vaccine trials underway in the United States and the United Kingdom - and considering various drugs for possible treatments and prophylaxis. Here, we provide an overview of SARS-CoV-2 by analyzing its virology, epidemiology, and modes of transmission while examining the current progress of testing procedures and possible treatments through drugs and vaccines.
Databáze: OpenAIRE
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