17-[16,17-Dihydroxycyclooctatinyl]-hexaketide ester from Streptomyces sp. SR107
| Autor: | Chun-Hua Lu, Shan-Ren Li, Meng-Yu-Jie Liu |
|---|---|
| Rok vydání: | 2016 |
| Předmět: |
Magnetic Resonance Spectroscopy
Stereochemistry Ring (chemistry) 01 natural sciences Streptomyces Drug Discovery Bacteria Molecular Structure Strain (chemistry) biology 010405 organic chemistry Chemistry Esters General Medicine Carbon-13 NMR biology.organism_classification Anti-Bacterial Agents 0104 chemical sciences 010404 medicinal & biomolecular chemistry Complementary and alternative medicine Proton NMR Diterpenes Antibacterial activity Two-dimensional nuclear magnetic resonance spectroscopy Heteronuclear single quantum coherence spectroscopy |
| Zdroj: | Chinese Journal of Natural Medicines. 14:931-933 |
| ISSN: | 1875-5364 |
| DOI: | 10.1016/s1875-5364(17)30018-3 |
| Popis: | A new hexaketide acid esterified by the 17-hydroxyl group of 16,17-dihydroxycyclooctatin, namely 17-[16,17-dihydroxycyclooctatinyl]-hexaketide ester (1), a member of the group of rare bacterial diterpenes with a fused 5-8-5 ring system was isolated from strain Streptomyces sp. SR107. The structure was determined on the basis of its spectral data (1H NMR, 13C NMR, 1H-1H COSY, HSQC, HMBC, NOESY, IR and HR-ESI-MS). The antibacterial activity was also evaluated in this paper. |
| Databáze: | OpenAIRE |
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