Efficacy and tolerability of a local acting antiseptic agent in the treatment of vaginal dysbiosis during pregnancy
| Autor: | Theodor W. May, Gerd Neumann, Volker Briese, Juliane Waldschläger, Jörg Siebert, Bernd Gerber |
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| Rok vydání: | 2010 |
| Předmět: |
Adult
medicine.medical_specialty Adolescent Pyridines medicine.drug_class Birth weight Phenoxyethanol Young Adult chemistry.chemical_compound Obstetric Labor Premature Antiseptic Pregnancy Humans Medicine Pregnancy Complications Infectious Young adult business.industry Obstetrics Obstetrics and Gynecology General Medicine medicine.disease Treatment Outcome Tolerability chemistry Anti-Infective Agents Local Premature Birth Ethylene Glycols Female Imines Bacterial vaginosis business Dysbiosis |
| Zdroj: | Archives of Gynecology and Obstetrics. 283:585-590 |
| ISSN: | 1432-0711 0932-0067 |
| DOI: | 10.1007/s00404-010-1414-4 |
| Popis: | In the present study, the efficacy and tolerability of the local acting antiseptic octenidine hydrochloride/phenoxyethanol (OHP) for the treatment of vaginal dysbiosis (VD) and/or bacterial vaginosis (BV) in pregnancy and its potential influence on preterm births and low-weight newborns were examined. One-hundred nine pregnant women with increased pH values (>4.5) and BV characteristic symptoms were treated with OHP for 7 days and a second time in case of a recurrent pH increase. pH values were continuously controlled by women’s self-measurements. pH decreased to ≤4.5 in 67.9% of patients. Seven of 12 women (58.3%) treated again with OHP due to a recurrent pH increase finally reached the pH target (pH ≤ 4.5). No preterm birth occurred in the OHP group; no newborn had a birth weight |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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