Current anti-diabetes mechanisms and clinical trials using Morus alba L
| Autor: | Baosheng Zhao, Simin Tian, Mingmin Tang |
|---|---|
| Rok vydání: | 2016 |
| Předmět: |
Traditional medicine
fungi food and beverages Molecular mechanisms 04 agricultural and veterinary sciences Type 2 diabetes Biology lcsh:RZ409.7-999 medicine.disease 040401 food science Mulberry leaf Clinical trial Clinical trials 0404 agricultural biotechnology Complementary and alternative medicine Chemical agents Diabetes mellitus medicine Hypoglycemic Effects Anti-diabetes lcsh:Miscellaneous systems and treatments |
| Zdroj: | Journal of Traditional Chinese Medical Sciences, Vol 3, Iss 1, Pp 3-8 (2016) |
| ISSN: | 2095-7548 |
| DOI: | 10.1016/j.jtcms.2016.04.001 |
| Popis: | Backgrounds Diabetes mellitus, especially type 2 diabetes, with its fast-rising prevalence, has become a global epidemic. Mulberry (Morus alba L.) leaf has been known to have hypoglycemic effects since ancient times. In Asia mulberry leaf is used as tea to complement the treatment of diabetes mellitus. The methods by which mulberry leaf affects the body and its mechanism when combined with chemical agents have been studied extensively. Conclusions We summarize the possible mechanisms of the anti-diabetic effects of mulberry leaf based on extraction procedures, in vitro and in vivo experiments, and clinical trials. We also discuss the hypothesis that crosstalk and “critical nodes” may be useful for a deeper molecular understanding of the treatment and prevention of diabetes with mulberry leaf. |
| Databáze: | OpenAIRE |
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