Trichomonas vaginalisvirus: a review of the literature
Autor: | Arindam P. Ghosh, Christina A. Muzny, Keonte J Graves, Patricia Kissinger |
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Rok vydání: | 2019 |
Předmět: |
food.ingredient
030231 tropical medicine Trichomonas Infections Genome Viral Dermatology medicine.disease_cause Polymerase Chain Reaction Virus 03 medical and health sciences 0302 clinical medicine food Metronidazole Trichomonas vaginalis medicine Humans RNA Viruses Pharmacology (medical) RNA Double-Stranded Totiviridae 030304 developmental biology 0303 health sciences Trichomoniasis biology business.industry Public Health Environmental and Occupational Health RNA virus RNA-Dependent RNA Polymerase biology.organism_classification medicine.disease Virology Infectious Diseases Capsid RNA Viral Double-stranded RNA viruses Capsid Proteins Trichomonasvirus business |
Zdroj: | International Journal of STD & AIDS. 30:496-504 |
ISSN: | 1758-1052 0956-4624 |
Popis: | Trichomonas vaginalis (TV) is a parasitic protozoan responsible for the sexually transmitted infection trichomoniasis. Trichomonas vaginalis virus (TVV) is a nonsegmented, 4.5–5 kbp, double-stranded RNA virus, from the Totiviridae family, which inhabits TV. A capsid protein consisting of 120 subunits is covered in channels aiding in RNA release. TVV is closely associated with the Golgi complex and is transmitted vertically. TVV has four subspecies, TVV1, TVV2, TVV3, and TVV4. The clinical significance of TVV and its effect on the pathogenicity of TV is not well known. We performed a systematic review of the literature on TVV to better understand its clinical significance and its role in the pathogenesis of TV. |
Databáze: | OpenAIRE |
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