Nutritional Regulation of Mammary Gland Development and Milk Synthesis in Animal Models and Dairy Species
| Autor: | Christine Leroux, Yannick Faulconnier, Cathy Hue-Beauvais, Madia Charlier |
|---|---|
| Přispěvatelé: | Génétique Animale et Biologie Intégrative (GABI), Université Paris-Saclay-AgroParisTech-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), Unité Mixte de Recherche sur les Herbivores - UMR 1213 (UMRH), VetAgro Sup - Institut national d'enseignement supérieur et de recherche en alimentation, santé animale, sciences agronomiques et de l'environnement (VAS)-AgroSup Dijon - Institut National Supérieur des Sciences Agronomiques, de l'Alimentation et de l'Environnement-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE) |
| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
0301 basic medicine
mammary gland lcsh:QH426-470 [SDV]Life Sciences [q-bio] Mammary gland Physiology Review lactation Biology Mammary gland development 03 medical and health sciences Human health Mammary Glands Animal Nutrigenomics Lactation Genetics medicine Animals development Genetics (clinical) 2. Zero hunger milk business.industry Dietary composition 0402 animal and dairy science Gene Expression Regulation Developmental 04 agricultural and veterinary sciences Ruminants 040201 dairy & animal science Phenotype Animal Feed lcsh:Genetics 030104 developmental biology medicine.anatomical_structure nutrition Models Animal gene expression Livestock Animal Nutritional Physiological Phenomena Female business Milk component |
| Zdroj: | Genes Genes, MDPI, 2021, 12 (4), pp.523. ⟨10.3390/genes12040523⟩ Genes, Vol 12, Iss 523, p 523 (2021) |
| ISSN: | 2073-4425 |
| Popis: | International audience; In mammals, milk is essential for the growth, development, and health. Milk quantity and quality are dependent on mammary development, strongly influenced by nutrition. This review provides an overview of the data on nutritional regulations of mammary development and gene expression involved in milk component synthesis. Mammary development is described related to rodents, rabbits, and pigs, common models in mammary biology. Molecular mechanisms of the nutritional regulation of milk synthesis are reported in ruminants regarding the importance of ruminant milk in human health. The effects of dietary quantitative and qualitative alterations are described considering the dietary composition and in regard to the periods of nutritional susceptibly. During lactation, the effects of lipid supplementation and feed restriction or deprivation are discussed regarding gene expression involved in milk biosynthesis, in ruminants. Moreover, nutrigenomic studies underline the role of the mammary structure and the potential influence of microRNAs. Knowledge from three lactating and three dairy livestock species contribute to understanding the variety of phenotypes reported in this review and highlight (1) the importance of critical physiological stages, such as puberty gestation and early lactation and (2) the relative importance of the various nutrients besides the total energetic value and their interaction. |
| Databáze: | OpenAIRE |
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