Multifocal Langerhans Cell Histiocytosis: A Unique Presentation of Eosinophilic Granuloma with Intracranial Extension, Massive Lymphadenopathy, and Epstein-Barr Viral Infection in an Adolescent Female
| Autor: | Kumaran Mudaliar, Cruse Cw, Shamika Kayo Robinson, Wendy Kim, Eleanor Tung-Hahn, George Gibbons, Kent Wade Foster, Rebecca Tung |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
Pathology
medicine.medical_specialty Eosinophilic granuloma Single Case Lymphadenopathy Dermatology medicine.disease_cause Virus 030207 dermatology & venereal diseases 03 medical and health sciences 0302 clinical medicine Langerhans cell histiocytosis Intracranial extension lcsh:Dermatology medicine Epstein-Barr virus Cyst business.industry lcsh:RL1-803 medicine.disease Massive lymphadenopathy Epstein–Barr virus Multifocal Langerhans cell histiocytosis medicine.anatomical_structure 030220 oncology & carcinogenesis Scalp Presentation (obstetrics) business |
| Zdroj: | Case Reports in Dermatology Case Reports in Dermatology, Vol 13, Iss 1, Pp 28-35 (2021) |
| ISSN: | 1662-6567 |
| DOI: | 10.1159/000511488 |
| Popis: | We report the case of an otherwise healthy 17-year-old female who presented for surgical removal of an enlarging “atypical cyst” on her scalp. During subtotal excision, only friable serosanguinous translucent ribbons of tissue were found. A histopathologic diagnosis of Langerhans cell histiocytosis (LCH) was rendered and imaging studies revealed extradural invasion of the tumor. Within weeks, the patient also developed progressive lymphadenopathy with grossly elevated levels of Epstein-Barr virus viral capsid antigen antibody levels. This report aims to highlight a unique presentation of LCH with discussion of workup, management, and avoidance of potential surgical complications. |
| Databáze: | OpenAIRE |
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