Assessment of cardio-ankle vascular index in patients with abdominal aortic aneurysm: An observational study
| Autor: | Ahmet Çağrı Aykan, Mustafa Çetin, Ümit Menteşe, Ezgi Kalaycıoğlu |
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| Rok vydání: | 2020 |
| Předmět: |
Male
medicine.medical_specialty 030204 cardiovascular system & hematology 03 medical and health sciences 0302 clinical medicine Vascular Stiffness Predictive Value of Tests Internal medicine medicine Humans Radiology Nuclear Medicine and imaging In patient 030212 general & internal medicine Cardio-ankle vascular index Aged Ultrasonography business.industry General Medicine Middle Aged medicine.disease Prognosis Abdominal aortic aneurysm Cross-Sectional Studies Cardio Ankle Vascular Index Case-Control Studies Arterial stiffness Cardiology Surgery Observational study Female Cardiology and Cardiovascular Medicine business Aortic Aneurysm Abdominal |
| Zdroj: | Vascular. 29(2) |
| ISSN: | 1708-539X |
| Popis: | ObjectivesArterial stiffness is associated with major adverse cardiovascular events. The aim of this study is to investigate arterial stiffness by cardio-ankle vascular index (CAVI) in patients with abdominal aortic aneurysm (AAA).MethodsThis observational and cross-sectional study involved 59 subjects with AAA and 32 healthy subjects. All subjects underwent ultrasonography examination. CAVI was measured by VaSera-1000 CAVI instrument.ResultsMean abdominal aortic diameter of AAA patients and controls were 43.88 ± 9.28 mm and 20.43 ± 3.14 mm, consecutively. Baseline clinical characteristics of the patients and controls were similar for age, presence of hypertension, diabetes, dyslipidemia, coronary artery disease and smoking. Left ventricle ejection fraction and Left ventricle mass index (LVMI) were similar between groups. CAVI was significantly higher in patients with AAA than controls (9.74 ± 1.50 vs. 7.60 ± 1.07, p 8.3 had a sensitivity 89.8% and a specificity of 78.1% for predicting the presence of AAA in ROC analysis (area under curve = 0.897, 95%CI = 0.816–0.951, p ConclusionCAVI is increased in patients with AAA. Increased arterial stiffness may be a mechanical link between AAA, coronary artery disease and peripheral artery disease or a common mechanism effects the arterial stiffness, coronary artery disease, peripheral artery disease and AAA. Therefore, CAVI may be used as a valuable marker for risk stratification for the development of AAA in susceptible patients. |
| Databáze: | OpenAIRE |
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