Survival after pulmonary metastasectomy in colorectal cancer patients: does a history of resected liver metastases worsen the prognosis? A literature review
| Autor: | Jose Angel De Marcos Izquierdo, José Ignacio Emparanza, Borja Aguinagalde, Iker Lopez, Arantza Fernandez-Monge, Jon Zabaleta |
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| Rok vydání: | 2017 |
| Předmět: |
Oncology
Cancer Research medicine.medical_specialty Colorectal cancer colorectal cancer Review 030204 cardiovascular system & hematology liver lcsh:RC254-282 Metastasis 03 medical and health sciences 0302 clinical medicine Internal medicine medicine metastasis Prospective cohort study Lung Survival rate business.industry Hazard ratio Retrospective cohort study lcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens medicine.disease medicine.anatomical_structure 030220 oncology & carcinogenesis Metastasectomy business |
| Zdroj: | Cancer Biology & Medicine Cancer Biology & Medicine, Vol 14, Iss 3, Pp 281-286 (2017) |
| ISSN: | 2095-3941 |
| DOI: | 10.20892/j.issn.2095-3941.2017.0073 |
| Popis: | Objective : To assess the impact of past liver metastases on the survival duration of patients who are undergoing surgery for lung metastases.Methods : We conducted a review of literature published from 2007 to 2014. The studies were identified by searching PubMed, MEDLINE, and Embase and were supplemented by a manual search of the references listed by the retrieved studies. The following search terms were used: lung metastasectomy, pulmonary metastasectomy, lung metastases, and lung metastasis. We selected retrospective and prospective studies published from 2007 to 2014 on patients with lung metastases from colorectal cancer and were undergoing surgery with curative intent. We excluded reviews, studies that focused on surgical techniques, patients who were treated non-surgically, analyses of specific subgroups of patients, and those that did not report follow-up of the patients undergoing surgery. Results : We identified 28 papers that assessed survival after lung metastases, 21 of which were mostly retrospective studies that identified previous liver metastases to explore their impact on patient survival. In more than half of the papers analyzed (63.2%), patients with a history of resected liver metastases had a lower survival rate than those who did not have such a history, and the difference was statistically significant in eight of these studies. However, data were presented differently, and authors reported mean survival time, survival rates, or hazard ratios. Conclusions : A history of liver metastases seems to be a negative prognostic factor, but the individual data need to undergo a meta-analysis. |
| Databáze: | OpenAIRE |
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