Wound-Stimulating Effect of Homologous and Heterologous Cartilage
| Autor: | Irving F. Enquist, Jack C. Sabo |
|---|---|
| Rok vydání: | 1965 |
| Předmět: |
Wound Healing
medicine.medical_specialty business.industry Research Cartilage Transplantation Heterologous Biophysics Heterologous Biophysical Phenomena Rats Surgery medicine.anatomical_structure Species Specificity medicine Homologous chromosome Transplantation Homologous Pentobarbital anesthesia Wound healing business Immune mechanisms |
| Zdroj: | Archives of Surgery. 91:523 |
| ISSN: | 0004-0010 |
| DOI: | 10.1001/archsurg.1965.01320150153031 |
| Popis: | IT has been firmly established that bovine tracheal cartilage powder will speed the early healing of sutured, incised wounds and open, granulating wounds in normal rats, guinea pigs and mice. 1-5 Additional studies from this laboratory have shown a more dramatic effect in the wounds of diabetic rats. 6,7 To date, only heterologous cartilage powder has been investigated. Because McKhann 8 found that animals whose immune mechanisms had been stimulated healed less rapidly than did normal animals, it seemed appropriate to test the effect of homologous cartilage on wound healing and to compare this effect with that brought on by heterologous material. For completeness, autologous material should also have been tested, but practical factors limited such an investigation. Methods Male albino Wistar rats weighing from 140 to 200 gm (.03 to.04 lb) were housed in individual cages and maintained on a standard laboratory diet. Under intraperitoneal pentobarbital anesthesia, the animals |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|