Blood pressure evolution in young patients with acute ischemic stroke: a new model for understanding the natural course of spontaneous hypertension?
| Autor: | Fatima Pantiu, Ricardo Reisin, Claudia Uribe Roca, Sol Pacha, Manuel Fernandez Pardal, Pablo Bonardo, Glenda Ernst, Luciana Leon Cejas, Anibal Chertcoff |
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| Rok vydání: | 2017 |
| Předmět: |
Adult
Male medicine.medical_specialty Adolescent Blood Pressure 030204 cardiovascular system & hematology Prehypertension Brain Ischemia Brain ischemia Young Adult 03 medical and health sciences 0302 clinical medicine Risk Factors Internal medicine Humans Medicine Young adult Acute ischemic stroke Stroke Natural course business.industry General Neuroscience General Medicine Middle Aged Models Theoretical medicine.disease Blood pressure Hypertension Disease Progression Transient hypertension Physical therapy Cardiology Female business 030217 neurology & neurosurgery |
| Zdroj: | International Journal of Neuroscience. 128:140-145 |
| ISSN: | 1543-5245 0020-7454 |
| Popis: | Approximately 80% of patients suffering an acute ischemic stroke develop transient hypertension. The physiopathological mechanism remains unclear. Due to the lack of vascular risk factors, young adults could be a useful model for understanding blood pressure (BP) evolution in this setting.Patients between 18 and 55 years old admitted with an acute ischemic stroke were included. BP was evaluated during the following 48 h. Hypertension was defined as: systolic blood pressure (SBP) ≥140 mmHg or diastolic blood pressure (DBP) ≥90 mmHg. Patients were divided into two groups: RF group included those who had a previous vascular risk factor and/or other medical condition known to affect the autonomic function; noRF group included patients without any of the previously stated conditions.Thirty-nine patients were included: mean age: 44.26 years old, 21 were males (53.8%). Mean SBP and DBP at admission were 139.77 ± 5.35 mmHg (range: 90-243) and 84.44 ± 3.02 mmHg (range: 60-128), respectively; 43.58% patients were hypertensive at admission. SBP decreased significantly during the first 48 h (p = 0.044) for the entire population. RF group has higher SBP (p = 0.009) and DBP (p = 0.011) at admission than the noRF group.Most patients were normotensive at admission and BP fell spontaneously despite BP at admission. Young patients without medical conditions that could alter the autonomic system function could be a useful model for understanding acute hypertension in ischemic stroke. |
| Databáze: | OpenAIRE |
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