Serum proteome profile in LT4-euthyroid thyroidectomized patients is correlated with free- triiodothyronine (FT3) levels

Autor: Landi, Claudia, Cantara, Silvia, Enxhi Shaba, Marzocchi, Carlotta, Maino, Fabio, Carleo, Alfonso, Giuseppe, Fabrizio Di, Angelucci, Stefania, Bini, Luca, Castagna, Maria Grazia
Rok vydání: 2021
Předmět:
DOI: 10.5281/zenodo.4419772
Popis: In patients undergoing thyroidectomy one of the goals of post-surgical follow-up is the correct manteinance of thyroid hormone levels by replacement therapy with levo thyroxine. Nevertheless, some patients complin of symptoms of hypothyroidism despite normal values of thyroid-stimulating hormone (TSH). We aim to investigate by a proteomic approach the serum proteome profile of thyroidectomized patients with reduced or unchanged FT3 levels on LT4-therapy to demonstrate that the lower post-surgical FT3 levels could be associated with tissue hypothiroidism.  
Databáze: OpenAIRE