Changes in ocular pulse amplitude and choroidal thickness in childhood obesity patients with and without insulin resistance
| Autor: | Gozde Aksoy Aydemir, Abdulvahit Aşik, Semih Bolu, Emre Aydemir |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
Pediatric Obesity
medicine.medical_specialty Choroid business.industry General Medicine medicine.disease Obesity Childhood obesity Tonometry Ocular Ophthalmology Insulin resistance medicine Humans Population study Prospective Studies Enhanced depth imaging Insulin Resistance Child Prospective cohort study business Body mass index Intraocular Pressure Tomography Optical Coherence Ct measurements |
| Zdroj: | European Journal of Ophthalmology. 32:2018-2025 |
| ISSN: | 1724-6016 1120-6721 |
| DOI: | 10.1177/11206721211039337 |
| Popis: | Purpose: To compare choroidal thickness (CT) and ocular pulse amplitude (OPA) in childhood obesity with insulin resistance (IR) and without IR. Methods: Seventy-three childhood obesity and 62 healthy children, who were both age-matched and gender-matched, comprised the study population in this prospective study. Obesity was determined as having a body mass index (BMI) – standard deviation (SD) score that was > 2 SD. Intraocular pressure (IOP) and OPA were measured using a dynamic contour tonometer. The CT measurements were performed using enhanced depth imaging optical coherence tomography at three locations, comprising at the fovea, at a position 500 µm nasal, and also at a position 500 µm temporal to the fovea. Results: Mean BMI value was 28.72 ± 4.85 in the patients with childhood obesity and 21.47 ± 1.14 in the control group. The mean IOP and OPA values were determined 15.90 ± 2.30 and 14.10 ± 2.16 mm Hg, 1.50 ± 0.28 and 1.74 ± 0.32 mm Hg in the patients with childhood obesity and the control group, respectively ( p 0.005). Conclusions: Our results showed that both OPA and CT values were significantly decreased in childhood obesity patients. We suggest further studies to verify longitudinal changes in OPA and CT, as also the evaluation of these parameters in other populations. |
| Databáze: | OpenAIRE |
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