Iron Deficiency Is a Determinant of Functional Capacity and Health-related Quality of Life 30 Days After an Acute Coronary Syndrome
| Autor: | Consol Ivern, Cosme García-García, Oona Meroño, Mercè Cladellas, Paula Poveda, Núria Ribas-Barquet, Josep Comín-Colet, Salvador Orient, Lluís Recasens, Joan Vila, Victor Bazan, Cristina Enjuanes |
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| Rok vydání: | 2017 |
| Předmět: |
Male
medicine.medical_specialty Acute coronary syndrome Time Factors Visual analogue scale Disease 030204 cardiovascular system & hematology 03 medical and health sciences 0302 clinical medicine Quality of life Internal medicine medicine Humans Prospective Studies 030212 general & internal medicine Acute Coronary Syndrome Treadmill Aged Aged 80 and over Exercise Tolerance business.industry Iron Deficiencies Recovery of Function General Medicine Iron deficiency Middle Aged Exercise capacity medicine.disease humanities Heart failure Quality of Life Physical therapy Female business |
| Zdroj: | Revista Española de Cardiología (English Edition). 70:363-370 |
| ISSN: | 1885-5857 |
| DOI: | 10.1016/j.rec.2016.10.004 |
| Popis: | Iron deficiency (ID) is a prevalent condition in patients with ischemic heart disease and heart failure. Little is known about the impact of ID on exercise capacity and quality of life (QoL) in the recovery phase after an acute coronary syndrome (ACS).Iron status and its impact on exercise capacity and QoL were prospectively evaluated in 244 patients 30 days after the ACS. QoL was assessed by the standard EuroQoL-5 dimensions, EuroQoL visual analogue scale, and Heart-QoL questionnaires. Exercise capacity was analyzed by treadmill/6-minute walk tests. The effect of ID on cardiovascular mortality and readmission rate was also investigated.A total of 46% of the patients had ID. These patients had lower exercise times (366±162 vs 462±155seconds; P.001), metabolic consumption rates (7.9±2.9 vs 9.3±2.6 METS; P=.003), and EuroQoL-5 dimensions (0.76±0.25 vs 0.84±0.16), visual analogue scale (66±16 vs 72±17), and Heart-QoL (1.9±0.6 vs 2.2±0.6) scores (P.05). ID independently predicted lower exercise times (OR, 2.9; 95%CI, 1.1-7.6; P=.023) and worse QoL (OR, 1.9; 95%CI, 1.1-3.3; P.001) but had no effect on cardiovascular morbidity or mortality.ID, a prevalent condition in ACS patients, results in a poorer mid-term functional recovery, as measured by exercise capacity and QoL. |
| Databáze: | OpenAIRE |
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