Asymmetries in initiation of aiming movements in schizophrenia
| Autor: | Francesco Lacquaniti, Cinzia Niolu, Alberto Siracusano, Daniele Nico, Giulia Lisi, Elena Daprati, Michele Ribolsi |
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| Rok vydání: | 2018 |
| Předmět: |
Adult
Male medicine.medical_specialty Cognitive Neuroscience Aiming movements Hemispheric lateralization Negative symptoms Psychomotor slowing Schizophrenia Experimental and Cognitive Psychology Motor Activity Settore BIO/09 Motor symptoms Functional Laterality 050105 experimental psychology Lateralization of brain function Young Adult 03 medical and health sciences Behavioral Neuroscience 0302 clinical medicine Physical medicine and rehabilitation medicine Humans 0501 psychology and cognitive sciences hemispheric lateralization Settore MED/25 - Psichiatria 05 social sciences Healthy subjects Motor control Middle Aged Hand medicine.disease schizophrenia aiming movements Female Psychology Psychomotor Performance 030217 neurology & neurosurgery |
| Zdroj: | Neuropsychologia. 109:200-207 |
| ISSN: | 0028-3932 |
| DOI: | 10.1016/j.neuropsychologia.2017.12.030 |
| Popis: | Several studies have reported motor symptoms in schizophrenia (SCZ), in some cases describing asymmetries in their manifestation. To date, biases were mainly reported for sequential movements, and the hypothesis was raised of a dopamine-related hemispheric imbalance. Aim of this research is to better characterize asymmetries in movement initiation in SCZ by exploring single actions. Fourteen SCZ patients and fourteen healthy subjects were recruited. On a trial-by-trial basis, participants were instructed to reach for one of eight possible targets. Measures of movement initiation and execution were collected. Starting point, target and moving limb were systematically varied to check for asymmetric responses. Results showed that SCZ patients, besides being overall slower than controls, additionally presented with a bias affecting both the moving hand and the side from which movements were initiated. This finding is discussed in relation to hemispheric lateralization in motor control. |
| Databáze: | OpenAIRE |
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