The role of lymphadenectomy in the management of renal cell carcinoma
Autor: | Glen W. Barrisford, Boris Gershman, Michael L. Blute |
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Rok vydání: | 2014 |
Předmět: |
Oncology
Nephrology medicine.medical_specialty business.industry Urology medicine.medical_treatment Lymph node disease Disease Management Retrospective cohort study medicine.disease Kidney Neoplasms Nephrectomy Increased risk Renal cell carcinoma Lymphatic Metastasis Internal medicine medicine Humans Lymph Node Excision Lymphadenectomy Lymph Nodes Risk assessment business Carcinoma Renal Cell |
Zdroj: | World Journal of Urology. 32:643-649 |
ISSN: | 1433-8726 0724-4983 |
DOI: | 10.1007/s00345-014-1294-5 |
Popis: | The role of lymphadenectomy in the management of renal cell carcinoma has been established in staging but is less well defined as a therapeutic maneuver. Level one evidence suggests no survival benefit or increased complication rate with lymphadenectomy when performed concurrently with radical nephrectomy. However, several retrospective studies have identified a survival benefit when patients with increased risk of micrometastatic lymph node disease undergo lymphadenectomy. We perform a selective review of the literature and present the historical basis, risk assessment, use and development of nodal templates, and therapeutic benefits associated with the use of lymphadenectomy in the management of renal cell carcinoma. |
Databáze: | OpenAIRE |
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