The role of lymphadenectomy in the management of renal cell carcinoma

Autor: Glen W. Barrisford, Boris Gershman, Michael L. Blute
Rok vydání: 2014
Předmět:
Zdroj: World Journal of Urology. 32:643-649
ISSN: 1433-8726
0724-4983
DOI: 10.1007/s00345-014-1294-5
Popis: The role of lymphadenectomy in the management of renal cell carcinoma has been established in staging but is less well defined as a therapeutic maneuver. Level one evidence suggests no survival benefit or increased complication rate with lymphadenectomy when performed concurrently with radical nephrectomy. However, several retrospective studies have identified a survival benefit when patients with increased risk of micrometastatic lymph node disease undergo lymphadenectomy. We perform a selective review of the literature and present the historical basis, risk assessment, use and development of nodal templates, and therapeutic benefits associated with the use of lymphadenectomy in the management of renal cell carcinoma.
Databáze: OpenAIRE