Development and preliminary evaluation of the QUALIKO: An observational quality of life instrument for patients with Korsakoff's syndrome

Autor: Yvonne C M Rensen, Roy P. C. Kessels, Jorrit F. Postma, Peter M. ten Klooster
Přispěvatelé: Psychology, Health & Technology
Rok vydání: 2020
Předmět:
Male
Quality of life
Alzheimer`s disease Donders Center for Medical Neuroscience [Radboudumc 1]
Psychometrics
Mokken scale
Nursing homes
lcsh:Computer applications to medicine. Medical informatics
03 medical and health sciences
All institutes and research themes of the Radboud University Medical Center
0302 clinical medicine
Surveys and Questionnaires
medicine
Humans
Reliability (statistics)
Aged
Neuro- en revalidatiepsychologie
030214 geriatrics
Research
Neuropsychology and rehabilitation psychology
Public Health
Environmental and Occupational Health
Reproducibility of Results
General Medicine
Middle Aged
Korsakoff’s syndrome
medicine.disease
Test (assessment)
Korsakoff Syndrome
Caregivers
lcsh:R858-859.7
Normative
Female
Observational study
Korsakoff's syndrome
Psychology
030217 neurology & neurosurgery
Clinical psychology
Zdroj: Health and Quality of Life Outcomes, 18
Health and quality of life outcomes, 18(1):244. BioMed Central
Health and Quality of Life Outcomes
Health and Quality of Life Outcomes, Vol 18, Iss 1, Pp 1-12 (2020)
ISSN: 1477-7525
DOI: 10.1186/s12955-020-01463-4
Popis: Background To develop a Korsakoff-specific measure of quality of life (QoL), to be rated by professional caregivers, and to field-test its psychometric properties in a sample of patients with Korsakoff’s syndrome (KS) living in a specialized nursing home. Methods A research version of the QUALIKO was developed based on an existing instrument for dementia (the QUALIDEM), literature review and two rounds of surveys among expert professionals involved in the care for patients with KS. Next, QoL was independently rated using the preliminary QUALIKO for 77 patients with KS by two primary caregivers. Results The research QUALIKO consisted of 48 items describing observable behaviors across ten aspects of QoL relevant to patients with KS. Six items demonstrated poor scalability in the field test. The remaining 42 items all formed subscales with moderate to strong scalability according to Mokken scale analysis. Reliability was acceptable to good across both raters for all subscales (Mokken rho’s = 0.70–0.90), except for the two 2-item subscales of negative affect and positive self-image (Mokken rho’s = 0.47–0.71). Inter-observer agreement was excellent for five subscales (ICCs = 0.75–0.89) and fair to moderate for the other five subscales (ICCs = 0.59–0.72). The multidimensional internal structure was confirmed and all subscales were significantly correlated with primary caregivers’ global ratings of QoL except for positive self-image. Missing item values were low and floor and ceiling effects acceptable for most subscales. Conclusions The QUALIKO holds promise as a feasible, reliable, and valid measure of QoL in residential KS patients. Future research in larger samples is needed to confirm the psychometric dimensionality of the instrument, to gather normative data and to examine its test-retest reliability.
Databáze: OpenAIRE
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