A combination of alfentanil-lidocaine-propofol provides better intubating conditions than fentanyl-lidocaine-propofol in the absence of muscle relaxants
| Autor: | Dabbous A, Tonine Bartelmaos, Samar Jabbour-Khoury, Laudia B. Rizk, Mohamad F. El-Khatib, Anis Baraka, Naji M. Abou Jalad |
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| Rok vydání: | 2003 |
| Předmět: |
Adult
Male medicine.medical_specialty Lidocaine medicine.drug_class Muscle Relaxation medicine.medical_treatment Blood Pressure Fentanyl Double-Blind Method Heart Rate Intubation Intratracheal medicine Humans Intubation Anesthetics Local Alfentanil Propofol Muscle Relaxants Central Local anesthetic business.industry Tracheal intubation General Medicine Surgery Analgesics Opioid Oxygen Anesthesiology and Pain Medicine Cholecystectomy Laparoscopic Jaw Opioid Anesthesia Female business Anesthetics Intravenous medicine.drug |
| Zdroj: | Canadian Journal of Anesthesia/Journal canadien d'anesthésie. 50:116-120 |
| ISSN: | 1496-8975 0832-610X |
| Popis: | To compare the ease of tracheal intubation without the use of muscle relaxants following an alfentanil-lidocaine-propofol sequence vs a fentanyl-lidocaine-propofol sequence.In 80 ASA I and II adult patients undergoing elective laparoscopic surgery, we compared the intubating conditions following alfentanil 20 microg x kg(-1), lidocaine 1.5 mg x kg(-1), propofol 3 mg x kg(-1) (Group I; n = 40) vs fentanyl 2 microg x kg(-1), lidocaine 1.5 mg x kg(-1), propofol 3 mg x kg(-1) (Group II; n = 40). The intubating conditions were scored by jaw relaxation, vocal cord position and response to intubation, as well as by blood pressure and heart rate changes. The intubating conditions were good or excellent in 95% of patients in Group I vs 62.5% of patients in Group II (P0.05). Blood pressure decreased from a preinduction value of 86 +/- 13 mmHg to 72 +/- 28 mmHg and 74 +/- 19 mmHg in Group I, and from 85 +/- 12 mmHg to 78 +/- 15 mmHg and 78 +/- 12 mmHg in Group II, one and five minutes following intubation (P0.05). This drop in blood pressure was not different between the two groups.An alfentanil-lidocaine-propofol sequence offers significantly better intubating conditions than a fentanyl-lidocaine-propofol sequence in healthy adult patients. |
| Databáze: | OpenAIRE |
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