Dietary Folate Intake Is Negatively Associated with Excess Body Weight in Brazilian Graduates and Postgraduates (CUME Project)
Autor: | Helena Maria Pinheiro Sant’Ana, Lílian Lelis Lopes, Fernando Luiz Pereira de Oliveira, Helen Hermana Miranda Hermsdorff, Adriano Marçal Pimenta, Gabriela A. Pereira, Josefina Bressan |
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Rok vydání: | 2019 |
Předmět: |
Adult
Male 0301 basic medicine Vitamin Folate obesity Universities Homocysteine B vitamins lcsh:TX341-641 body mass index 030209 endocrinology & metabolism folate Article 03 medical and health sciences chemistry.chemical_compound Folic Acid 0302 clinical medicine Animal science Humans Medicine Obesity Vitamin B12 Students Body mass index 030109 nutrition & dietetics Nutrition and Dietetics business.industry homocysteine Middle Aged Overweight medicine.disease Confidence interval Diet Cross-Sectional Studies chemistry Cohort Female business lcsh:Nutrition. Foods and food supply Brazil Food Science |
Zdroj: | Nutrients LOCUS Repositório Institucional da UFV Universidade Federal de Viçosa (UFV) instacron:UFV Nutrients, Vol 11, Iss 3, p 518 (2019) Volume 11 Issue 3 Repositório Institucional da UFOP Universidade Federal de Ouro Preto (UFOP) instacron:UFOP |
ISSN: | 2072-6643 |
DOI: | 10.3390/nu11030518 |
Popis: | Folate, vitamin B6, and vitamin B12 intake can be important regulators for obesity development. Thus, we investigated the possible association between the intake of these vitamins and the excess body weight or obesity prevalence in the participants of the Cohort of Universities in Minas Gerais (CUME project). This study analyzed cross-sectional data of 2695 graduates and postgraduates from universities in the state of Minas Gerais (801 men, 1894 women, ages 36.2 ± 9.4). The first step consisted of collecting data online, and the second step consisted of blood collecting in the subsample living in the city of Viç osa and its region (Minas Gerais). Excess body weight and obesity prevalence were 38.1% and 10.1%, respectively. Inadequate intake of folate, B6, and B12 were 12, 6.3, and 11.1%, respectively. Beans/lentils and French bread presented the highest contribution to folate intake (23.45% and 10.01%, respectively). Those individuals in the third tertile for folate intake (&ge 511.12 &mu g/d) had a lower excess body weight [prevalence ratio (PR): 0.79, confidence interval (CI): 0.71&ndash 0.8] and obesity prevalence (PR: 0.60, CI: 0.45&ndash 0.78). These associations were maintained when the sample was categorized by sex. In addition, serum folate was positively associated with dietary folate (p for trend = 0.032) and negatively associated with serum homocysteine (p for trend = 0.003) in the subsample. Dietary folate intake was negatively associated with excess body weight and obesity in CUME participants, indicating the relevance of this vitamin dietary assessment. |
Databáze: | OpenAIRE |
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