Does Preoperative Hydration Affect Postoperative Nausea and Vomiting? A Randomized, Controlled Trial

Autor: Tayfun Adanir, Uğur Özgürbüz, Fahri Altin, Murat Aksun, Atilla Şencan
Rok vydání: 2008
Předmět:
Zdroj: Journal of Laparoendoscopic & Advanced Surgical Techniques. 18:1-4
ISSN: 1557-9034
1092-6429
DOI: 10.1089/lap.2007.0019
Popis: It has been suggested that relative hypovolemia due to overnight fasting may result in postoperative nausea and vomiting (PONV). The aim of this study was to investigate the effect of preoperative and intraoperative hydration (the necessary amount of fluid preoperatively to cover the fluid deficit) on PONV.Two hundred and ten consecutive patients who underwent elective laparoscopic cholecystectomy with The American Society of Anesthesiologists (ASA)-I physical statuses were studied prospectively. The patients were randomly assigned to one of two groups, each having 104 patients. Group 1 received intraoperative volume replacement, but Group-II received preoperative volume replacement. Postoperative antiemetic efficacy was assessed by the ratio of the patients that require an antiemetic over the whole group.The PONV was significantly less detected in the preoperative replacement group (48% in Group 2) than the intraoperative one (64% in Group 1) (P = 0.019).PONV was reduced when the fluid deficit was replaced preoperatively.
Databáze: OpenAIRE