Previous caesarean section is associated with lower subsequent in vitro fertilization live birth rates
Autor: | Lucette A. J. van der Westerlaken, Nicole F. Klijn, Juan D. N. Diaz de Pool, Marjolein M. van den Tweel, Leoni A. Louwe |
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Jazyk: | angličtina |
Rok vydání: | 2019 |
Předmět: |
Adult
medicine.medical_specialty Pregnancy Rate medicine.medical_treatment 030209 endocrinology & metabolism Fertilization in Vitro live birth 03 medical and health sciences 0302 clinical medicine Pregnancy In vitro fertilization medicine Humans Caesarean section Birth Rate reproductive and urinary physiology Retrospective Studies embryo transfer 030219 obstetrics & reproductive medicine In vitro fertilisation Cesarean Section Vaginal delivery business.industry Obstetrics Obstetrics and Gynecology Retrospective cohort study General Medicine Odds ratio Embryo transfer Reproductive Medicine caesarean section embryonic structures Population study Female Live birth business |
Zdroj: | Human Fertility. TAYLOR & FRANCIS LTD Human Fertility |
Popis: | This retrospective cohort study examines the association between previous mode of delivery and subsequent live birth rate in women who become pregnant after in vitro fertilization (IVF) or intra cytoplasmic sperm injection (ICSI) after their first delivery. The study included 112 women with a previous caesarean section and 418 women with a previous vaginal delivery, and a total of 1588 embryo transfers between January 2005 and June 2016 (Leiden University Medical Centre, the Netherlands). The mean age was 35 years and mean number of embryos transferred per attempt, 1.18. The study population included a total of 429 pregnancies resulting in 296 live births. The crude odds ratio for a subsequent live birth per embryo transfer was 0.60 (CI; 0.44 to 0.83, p = 0.002) in women with a previous caesarean section compared to women with a previous vaginal delivery. After adjustment for age, fresh/frozen-thawed embryo transfer and quality of the embryo, the odds ratio was 0.64 (CI; 0.46 to 0.89, p = 0.01). It was concluded that in subfertile women trying to achieve a subsequent pregnancy with IVF or ICSI, a history of caesarean section was associated with a reduced live birth rate per embryo transfer compared to women with a history of one previous vaginal delivery. |
Databáze: | OpenAIRE |
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