Neuropathic diabetic foot ulcers treated with cerium dioxide nanoparticles: A case report
| Autor: | Nazarii Kobyliak, Ludovico Abenavoli, Mykola Ya Spivak, Dmytro Kyriienko, Liudmyla Kononenko |
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| Rok vydání: | 2019 |
| Předmět: |
Male
medicine.medical_specialty Endocrinology Diabetes and Metabolism Topical treatment 02 engineering and technology Oxidative damage 03 medical and health sciences Animal model Diabetes mellitus Internal Medicine medicine Humans 030304 developmental biology Wound Healing 0303 health sciences business.industry Cerium General Medicine Middle Aged Prognosis 021001 nanoscience & nanotechnology medicine.disease Diabetic foot Dermatology Diabetic Foot Traumatic injury Diabetes Mellitus Type 2 Nanoparticles Neuropathic ulcers 0210 nano-technology business Wound healing |
| Zdroj: | Diabetes & Metabolic Syndrome: Clinical Research & Reviews. 13:228-234 |
| ISSN: | 1871-4021 |
| Popis: | Wound healing in diabetes is frequently impaired and its treatment remains a challenge. The ability of topical application of cerium (Ce) dioxide nanoparticles (CNPs) to accelerate wound healing in an animal model provides a rationale to develop this technology for use in humans affected by traumatic injury, diabetes and burns. We first described a case report of successful topical treatment of neuropathic diabetic foot ulcers with novel gel containing CNPs. The CNPs has bacteriostatic activity, anti-inflammatory properties and can penetrated into the wound tissue and reduced oxidative damage therefore protect regenerative tissue, suggesting a therapeutic potential for topical treatment of diabetic foot ulcers. |
| Databáze: | OpenAIRE |
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