Effect of vitamin B6 and magnesium on renal deposition of calcium oxalate induced by ethylene glycol administration
| Autor: | Stanley N. Gershoff, S. B. Andrus |
|---|---|
| Rok vydání: | 1962 |
| Předmět: |
Calcium metabolism
Ethylene Glycol Oxalates Calcium Oxalate Magnesium Inorganic chemistry Calcium oxalate chemistry.chemical_element Kidney metabolism Urine Water-Electrolyte Balance Kidney General Biochemistry Genetics and Molecular Biology Oxalate Vitamin B 6 Solvent chemistry.chemical_compound Glycols chemistry Humans Calcium Ethylene glycol Nuclear chemistry |
| Zdroj: | Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.). 109 |
| ISSN: | 0037-9727 |
| Popis: | SummaryOral administration of ethylene glycol to rats and the resultant renal de-position of calcium oxalate were studied in terms of dietary levels of Vit. B6 and magnesium. Under the conditions of these experiments partial protection against oxalate deposition was achieved with excessive dietary Vit. B6 while complete protection resulted when large amounts of MgO were fed. The in vivo oxidation of ethylene glycol to CO2 was found to be related to amount of Vit. B6 administered. Dietary magnesium levels, however, did not affect oxidation of ethylene glycol and it is suggested that dietary magnesium protects against renal deposition of calcium oxalate by altering the solvent characteristics of urine. |
| Databáze: | OpenAIRE |
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