Use of topical tranexamic acid in primary total hip arthroplasty. Efficiency and safety. Our experience
| Autor: | J.V. Díaz-Martínez, Eduardo Sánchez-Alepuz, A. Collado-Sánchez, I. Miranda, I. Peregrín-Nevado, Francisco J. Miranda |
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| Rok vydání: | 2020 |
| Předmět: |
Adult
Male medicine.medical_specialty Blood transfusion Administration Topical Arthroplasty Replacement Hip medicine.medical_treatment Blood Loss Surgical Prospective data 030204 cardiovascular system & hematology 03 medical and health sciences 0302 clinical medicine Clinical Protocols medicine Humans Blood Transfusion Orthopedics and Sports Medicine Prospective Studies Aged 030222 orthopedics Administración tópica Artroplastia total cadera Topical administration Total hip arthroplasty Tranexamic acid Ácido tranexámico business.industry Femoral canal Middle Aged Antifibrinolytic Agents Surgery Treatment Outcome medicine.anatomical_structure Tranexamic Acid Acido tranexamico Female business Tranexamic acid medicine.drug Total hip arthroplasty |
| Zdroj: | Revista espanola de cirugia ortopedica y traumatologia r-IIS La Fe. Repositorio Institucional de Producción Científica del Instituto de Investigación Sanitaria La Fe instname |
| ISSN: | 1888-4415 |
| Popis: | Background and aim Intravenous tranexamic acid has been shown to reduce bleeding and the need for transfusions in total hip arthroplasty, although it has a theoretical risk of producing thromboembolic phenomena. Recently some papers have been published using the topical application of tranexamic acid, but the ideal administration protocol has not yet been clearly defined. The aim of this paper was to demonstrate that our protocol of topical tranexamic acid is effective and safe. Methods Prospective data collection from a case series of 80 primary hip arthroplasties, in which the following topical tranexamic acid protocol is used: 1.5 g diluted to a total volume of 60 ml were administered, applying 20 ml in the acetabular bed, 20 ml in the femoral canal and 20 ml through the Redon drain, keeping it closed for 20 min. Results Eighty patients were operated. Preoperative haemoglobin 14.26 g/dL; preoperative haematocrit 42.39%. An average loss of 2.74 g/dL of haemoglobin and 8% of haematocrit was obtained. Eleven percent of the patients required transfusion, of whom 67% had known previous anaemia; only 3 patients without prior anaemia required transfusion (4%). There were no thromboembolic complications in our series. Conclusion The use of topical tranexamic acid was safe and effective in primary total hip arthroplasty, reducing the need for blood transfusion compared to that described in the literature in untreated patients. |
| Databáze: | OpenAIRE |
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