Impact of hepatitis B and C virus on kidney transplantation outcome
| Autor: | Mouquet C, C. Fretz, Pierre Coriat, Marc Olivier Bitker, Hadjira Benalia, Cheickna Sylla, Vincent Thibault, Pierre Opolon, Thierry Poynard, B Bernard, Philippe Mathurin, Jean-François Cadranel |
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| Rok vydání: | 1999 |
| Předmět: |
Adult
Male HBsAg medicine.medical_specialty Cirrhosis Population medicine.disease_cause Gastroenterology Postoperative Complications Internal medicine medicine Humans education Kidney transplantation Retrospective Studies Hepatitis B virus Analysis of Variance education.field_of_study Hepatitis B Surface Antigens Hepatology business.industry Graft Survival virus diseases Hepatitis B Prognosis medicine.disease Hepatitis C Kidney Transplantation Survival Analysis digestive system diseases Transplantation Treatment Outcome Case-Control Studies Immunology Female Kidney Diseases Hepatitis C Antigens business Kidney disease |
| Zdroj: | Hepatology. 29:257-263 |
| ISSN: | 1527-3350 0270-9139 |
| Popis: | The impact of hepatitis B (HBV) and C (HCV) on patient survival after kidney transplantation is controversial. The aims of this study were (1) to assess the independent prognostic values of HBsAg and anti-HCV in a large renal transplant population, (2) to compare infected patients with noninfected patients matched for factors possibly associated with graft and patient survival, and (3) to assess the prognostic value of biopsy-proven cirrhosis. Eight hundred thirty-four transplanted patients were included: 128 with positive HBsAg (group I), 216 with positive anti-HCV (group II), and 490 without serological markers of HBV and HCV (group III). Fifteen percent and 29% of patients were HBsAg-positive and anti-HCV-positive, respectively. Ten-year survivals of group I (55 +/- 6%) and group II (65 +/- 5%) were significantly lower than survival of group III (80 +/- 3%, P |
| Databáze: | OpenAIRE |
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