Radiofrequency Ablation Followed by Percutaneous Ethanol Ablation Leading to Long-Term Remission of Hyperparathyroidism
| Autor: | Arun S Menon, R. Vasukutty Jayakumar, Harish Kumar, Vadayath Usha Menon, Mohan T Shenoy, Vasantha Nair, Praveen V Pavithran, Srikanth Moorthy, P. K. Nazar, Nithya Abraham, Nisha Bhavani |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2017 |
| Předmět: |
Parathyroidectomy
medicine.medical_specialty Percutaneous Parathyroid Bone and Mineral Metabolism Radiofrequency ablation Endocrinology Diabetes and Metabolism medicine.medical_treatment Case Reports 030218 nuclear medicine & medical imaging Cerebral palsy law.invention 03 medical and health sciences 0302 clinical medicine parathyroid adenoma law medicine 030212 general & internal medicine Parathyroid adenoma Muscle contracture Hyperparathyroidism business.industry hypercalcemia medicine.disease Surgery Anesthetic radiofrequency ablation business medicine.drug |
| Zdroj: | Journal of the Endocrine Society |
| ISSN: | 2472-1972 |
| Popis: | A 30-year-old male with cerebral palsy and motor impairment presented with right femur fracture. He had gradually worsening mobility and contractures of all extremities for the preceding 5 years. Evaluation showed multiple vertebral and femoral fractures, severe osteoporosis, a large parathyroid adenoma, and parathormone (PTH) exceeding 2500 pg/mL. Because of poor general health and high anesthetic risk, parathyroidectomy was deemed impractical. Ultrasound-guided radiofrequency ablation (RFA) helped achieve 50% size reduction and PTH levels with better control of hypercalcemia. Later, as calcium and PTH remained elevated, percutaneous ethanol ablation was performed with resultant normalization of PTH and substantial symptomatic improvement. Two years later, he still remains normocalcaemic with normal PTH levels. We propose that RFA and percutaneous ethanol ablation be considered as effective short-term options for surgically difficult cases, which could even help achieve long-term remission. Although not previously reported, our case illustrates that both RFA and percutaneous ethanol ablation could be safely performed successively achieving long-term remission. Effective short-term options like radiofrequency ablation, percutaneous ethanol ablation, if offered for surgically difficult cases like ours, could achieve long-term remission of hyperparathyroidism. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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