Low-rate nerve stimulation during regional ischemia in the diagnosis of muscle glycogenosis
| Autor: | M LoMonaco, Enza Maria Valente, Margherita Milone, Pietro Attilio Tonali, Luca Padua |
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| Rok vydání: | 1996 |
| Předmět: |
Adult
Male medicine.medical_specialty Time Factors Adolescent Physiology Ischemia Neuromuscular transmission Action Potentials Stimulation Cellular and Molecular Neuroscience Muscular Diseases Reference Values Physiology (medical) Internal medicine Myasthenia Gravis medicine Humans Repetitive nerve stimulation Child Ulnar nerve Ulnar Nerve Aged business.industry Muscles Neuromuscular Diseases Middle Aged Glycogen Storage Disease medicine.disease Constriction Electric Stimulation Myasthenia gravis Compound muscle action potential Endocrinology Regional Blood Flow Cardiology Facilitation Female Neurology (clinical) business |
| Zdroj: | Scopus-Elsevier |
| ISSN: | 1097-4598 0148-639X |
| Popis: | Five patients with muscle glycogenoses (Gly), 30 normal subjects (NS), and 52 disease controls received 3 Hz repetitive stimulation of the ulnar nerve for 4 min (P-LRNS) during regional ischemia and during normal circulation. During regional ischemia, the compound muscle action potential (CMAP) of NS showed 8.5% (SE: 1.0) facilitation after 1 min of P-LRNS and 4.8 ± 1.5% facilitation after 4 min. Gly showed 8.1 ± 1.0% facilitation after 1 min of P-LRNS but −58.6 ± 6.9% depression after 4 min of P-LRNS. During normal circulation, in 18 NS and 4 Gly tested, the facilitation detected after 1 min of P-LRNS was unchanged until the end of stimulation. Compared with the mean ± 2 SD of NS, individual values of CMAP depression were abnormal in all Gly patients already by the 3rd min of ischemic P-LRNS. of disease controls, myasthenia gravis patients only showed a CMAP depression during ischemic P-LRNS which was distinguishable from that detected in Gly, being mainly induced by neuromuscular transmission block. © 1996 John Wiley & Sons, Inc. |
| Databáze: | OpenAIRE |
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