Complete genome analysis of hepatitis C virus subtypes 6t and 6u
| Autor: | Bart L. Haagmans, Saskia L. Smits, Yong Poovorawan, Suwanna Noppornpanth, Truong Xuan Lien, Albert D. M. E. Osterhaus |
|---|---|
| Přispěvatelé: | Virology |
| Rok vydání: | 2008 |
| Předmět: |
Canada
Genotype Hepacivirus Hepatitis C virus Molecular Sequence Data Emigrants and Immigrants Sequence Homology Genome Viral Viral Nonstructural Proteins medicine.disease_cause Genome Virus chemistry.chemical_compound Flaviviridae Viral Envelope Proteins SDG 3 - Good Health and Well-being Virology medicine Humans NS5B Phylogeny Genetics biology Viral Core Proteins Nucleic acid sequence virus diseases Sequence Analysis DNA Thailand biology.organism_classification Hepatitis C digestive system diseases Vietnam chemistry |
| Zdroj: | Journal of General Virology, 89, 1276-1281. Microbiology Society |
| ISSN: | 0022-1317 |
| Popis: | Hepatitis C virus (HCV) genomes exhibit high nucleotide sequence diversity. In this study, we performed complete genome sequence analysis of 11 HCV genotype 6 samples from Vietnam and Thailand. We identified nine HCV complete genomes belonging to subtypes 6a (D9), 6e (D42 and D88), 6f (TH52), 6i (TH24), 6l (D33), 6n (TH22 and TH31) and 6o (D85). Phylogenetic analysis of the core/E1 and NS5B regions from unclassified genotype 6 isolates from Asian immigrants in Canada revealed that two other viruses (D49 and D83) could be classified as novel candidates of HCV subtypes 6t and 6u. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|