Searching for the roots of the first free African American community

Autor: Leonor Gusmão, Masinda Nguidi, Javier Marrugo, Elizeu Fagundes de Carvalho, Verónica Gomes, Filipa Simão, Beatriz Martínez, António Amorim
Přispěvatelé: Instituto de Investigação e Inovação em Saúde
Jazyk: angličtina
Rok vydání: 2020
Předmět:
Male
0301 basic medicine
Adolescent
Population genetics
media_common.quotation_subject
Population
Black People
Blacks / genetics
lcsh:Medicine
Chromosomes
Human
Y / genetics
Colombia
030105 genetics & heredity
DNA
Mitochondrial
Polymorphism
Single Nucleotide
Article
03 medical and health sciences
Genetic drift
Phylogenetics
Genetics
Humans
Child
education
lcsh:Science
Phylogeny
media_common
mtDNA control region
African american
education.field_of_study
Chromosomes
Human
Y
African Americans / genetics
Multidisciplinary
Phylogenetic tree
Genetic Drift
lcsh:R
Black or African American
Phylogeography
030104 developmental biology
Geography
Haplotypes
Evolutionary biology
Child
Preschool
DNA
Mitochondrial / genetics
Genetic markers
lcsh:Q
Polymorphism
Single Nucleotide / genetics
Diversity (politics)
Zdroj: Scientific Reports, Vol 10, Iss 1, Pp 1-11 (2020)
Scientific Reports
ISSN: 2045-2322
DOI: 10.1038/s41598-020-77608-8
Popis: San Basilio de Palenque is an Afro-descendant community near Cartagena, Colombia, founded in the sixteenth century. The recognition of the historical and cultural importance of Palenque has promoted several studies, namely concerning the African roots of its first inhabitants. To deepen the knowledge of the origin and diversity of the Palenque parental lineages, we analysed a sample of 81 individuals for the entire mtDNA Control Region as well as 92 individuals for 27 Y-STRs and 95 for 51 Y-SNPs. The results confirmed the strong isolation of the Palenque, with some degree of influx of Native American maternal lineages, and a European admixture exclusively mediated by men. Due to the high genetic drift observed, a pairwise FST analysis with available data on African populations proved to be inadequate for determining population affinities. In contrast, when a phylogenetic approach was used, it was possible to infer the phylogeographic origin of some lineages in Palenque. Contradicting previous studies indicating a single African origin, our results evidence parental genetic contributions from widely different African regions. We thank all sample donors for their contribution to this work and all the people who helped with sample collection, namely, Regina Miranda from the Community of San Basilio de Palenque, the personnel of the Benkos Biojó Rural school, and Miguel Obeso from the etnoeducación program. This work was supported by the University of Cartagena and FPIT—Fundación para la promoción de la investigación y la tecnología del Banco de la República, Colombia (FPIT-388) and partially financed by FEDER—Fundo Europeu de Desenvolvimento Regional funds through the COMPETE 2020—Operacional Programme for Competitiveness and Internationalization (POCI), Portugal 2020, and by Portuguese funds through FCT—Fundação para a Ciência e a Tecnologia/Ministério da Ciência, Tecnologia e Inovação in the framework of the projects “Institute for Research and Innovation in Health Sciences” (POCI-01-0145-FEDER-007274). FS was supported by Fundação de Amparo à Pesquisa do Estado do Rio de Janeiro—FAPERJ (E-26/202.275/2019). LG was supported by Conselho Nacional de Desenvolvimento Científico e Tecnológico—CNPq (ref. 306342/2019-7), and Fundação de Amparo à Pesquisa do Estado do Rio de Janeiro—FAPERJ (CNE-2018). VG was supported by FCT, under the program contract provided in Decree-Law no.57/2016 of August 29. The IPATIMUP integrates the i3S research unit, which is partially supported by the Portuguese Foundation for Science and Technology.
Databáze: OpenAIRE
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