Three related near-haploid clones in a primary endometrioid carcinoma of the ovary

Autor: Chandrika Sreekantaiah, Avery A. Sandberg, Ulla Crickard, Kent Crickard, Mahmood Yoonessi
Rok vydání: 1990
Předmět:
Zdroj: Gynecologic oncology. 38(2)
ISSN: 0090-8258
Popis: We report the cytogenetic findings in a primary endometrioid carcinoma of the ovary from a 29-year-old woman. Three clones with counts of 30, 29, and 27 chromosomes were observed. The predominant clone had 29 chromosomes and the following karyotype: 29, X, −X, −3, −3, +der(3)ins(3;?) (q21;?), −4, −5, −6, −8, −9, −11, −13, −14, −15, −16, −17, −18, −19, −21, −22, +mar. The clone with 30 chromosomes had an additional marker in the form of a minute chromosome, and the clone with 27 chromosomes was monosomic for chromosomes 12 and 20 also. Interestingly, there was no nullisomy of any of the Chromosomes.
Databáze: OpenAIRE