Pulmonary Hypertension and Transbronchial Lung Biopsy: Does It Increase the Risk of Hemorrhage?
| Autor: | Caitlin Hodge, Bilal Lashari, Rajesh Kumar Patel, Megumi Asai, Charis Ripley-Hager, Waed Alswealmeen |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
medicine.medical_specialty
Pulmonology medicine.diagnostic_test transbronchial lung biopsy business.industry Significant difference Transbronchial lung biopsy General Engineering complication 030204 cardiovascular system & hematology medicine.disease Pulmonary hypertension Surgery 03 medical and health sciences 0302 clinical medicine Bronchoscopy pulmonary hypertension Biopsy Medicine Major complication hemorrhage Risk factor business Complication 030217 neurology & neurosurgery |
| Zdroj: | Cureus |
| ISSN: | 2168-8184 |
| DOI: | 10.7759/cureus.9084 |
| Popis: | Background Bronchoscopy with transbronchial lung biopsy (TBLB) is commonly used as a diagnostic tool for pulmonary disease. Hemorrhage is a major complication of TBLB. While pulmonary hypertension (PH) is considered a risk factor, evidence supporting this is limited. In this study, we compare complications of TBLB in patients with PH to those without PH. Material and methods We performed a retrospective review of patients who underwent TBLB in our institution from January 2010 to May 2016. PH and non-PH groups were compared with respect to patient demographics, biopsy guidance, number of lobes biopsied (single or multiple), positive pressure ventilation, pre- and post-procedure diagnoses, and complications. Complications were defined as major hemorrhage, prolonged intubation, and reintubation within 72 hours from TBLB. Results The PH group had 45 patients with a mean age of 71 ± 14 years, and the non-PH group had 349 patients with a mean age of 63 ± 14 years. There were no significant differences with regards to gender, pre-procedure anticoagulation and antiplatelet agents, biopsy guidance, or number of lobes biopsied (p > 0.371). There was no significant difference in the occurrence of major hemorrhage between the two groups (p = 0.491). Prolonged intubation occurred more frequently in the PH group (p = 0.007). Conclusions There appears to be no increased risk of post-procedure hemorrhage with TBLB in patients with mild PH. There is, however, an increased risk of post-procedure prolonged intubation in these patients. |
| Databáze: | OpenAIRE |
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