Brownian motion, fluctuation and life
| Autor: | Seiji Esaki, Toshio Yanagida, Yoshiharu Ishii, Tsutomu Murata, Masahiro Ueda |
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| Rok vydání: | 2007 |
| Předmět: |
Models
Molecular Statistics and Probability Protein Conformation Biophysics Kinesins Myosins Kinetic energy Models Biological Biophysical Phenomena General Biochemistry Genetics and Molecular Biology Quantitative Biology::Subcellular Processes Motor protein Motion Thermal Molecular motor Animals Molecule Statistical physics Brownian motion chemistry.chemical_classification Physics Stochastic Processes Molecular Motor Proteins Systems Biology Applied Mathematics Biomolecule Proteins General Medicine Polarization (waves) Actins chemistry Modeling and Simulation Thermodynamics Physical chemistry Signal Transduction |
| Zdroj: | Biosystems. 88:228-242 |
| ISSN: | 0303-2647 |
| Popis: | The measurements of dynamic behaviors of biomolecules in relation to their functions have been allowed using single molecule measurements. Thermal Brownian motion causes random step motion of motor proteins and structural fluctuation of protein molecules between multiple states. In hierarchic structure of life, the fluctuation is modulated. Random fluctuation is biased to directional motion and reactions as a result of interaction of proteins. The fluctuation of kinetic state of signaling proteins results in polarization and localization of cells. A recognition process in brain is also explained by the equation analogous to biochemical reaction at the molecular level. Thus dynamic processes originated from thermal motion may play an important role in activation processes in life. |
| Databáze: | OpenAIRE |
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