Anti-HL-A7 lymphocyte-dependent antibody
Autor: | E. B. Rosenberg, J. R. Wunderlich, J. Connolly, G. N. Rocentine |
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Rok vydání: | 1975 |
Předmět: |
Lymphocyte
Immunology Cell Biochemistry Antibodies Antigen-Antibody Reactions HLA Antigens Pregnancy Histocompatibility Antigens Genetics medicine Immunology and Allergy Cytotoxic T cell Humans Lymphocytes Antiserum biology Chemistry Immune Sera General Medicine Cytotoxicity Tests Immunologic Virology In vitro medicine.anatomical_structure biology.protein Female Adsorption Antibody |
Zdroj: | Tissue antigens. 6(1) |
ISSN: | 0001-2815 |
Popis: | Target cell specificity of a human cytotoxic lymphocyte-dependent antiserum correlated with the presence of HL-A7 on target cells. Target cells from 10 of 11 HL-A7-positive donors were damaged in vitro by this antiserum together with lymphocytes from normal donors. Target cells from six donors lacking HL-A7 were not damaged. Cytotoxic activity was removed by adsorption of the antiserum with lymphocytes from any one of four HL-A7-positive donors. Adsorption with lymphocytes from any one of three HL-A7-negative donors failed to eliminate cytotoxic activity. |
Databáze: | OpenAIRE |
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