Anti-HL-A7 lymphocyte-dependent antibody

Autor: E. B. Rosenberg, J. R. Wunderlich, J. Connolly, G. N. Rocentine
Rok vydání: 1975
Předmět:
Zdroj: Tissue antigens. 6(1)
ISSN: 0001-2815
Popis: Target cell specificity of a human cytotoxic lymphocyte-dependent antiserum correlated with the presence of HL-A7 on target cells. Target cells from 10 of 11 HL-A7-positive donors were damaged in vitro by this antiserum together with lymphocytes from normal donors. Target cells from six donors lacking HL-A7 were not damaged. Cytotoxic activity was removed by adsorption of the antiserum with lymphocytes from any one of four HL-A7-positive donors. Adsorption with lymphocytes from any one of three HL-A7-negative donors failed to eliminate cytotoxic activity.
Databáze: OpenAIRE