Does Beta-Blockade Reduce the Risk of Depression in Patients with Isolated Severe Extracranial Injuries?
| Autor: | Olle Ljungqvist, Eric J. Ley, Shahin Mohseni, Rebecka Ahl, Galinos Barmparas, Göran Wallin, Louis Riddez |
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| Rok vydání: | 2017 |
| Předmět: |
Adult
Male Risk medicine.medical_specialty Original Scientific Report Adrenergic beta-Antagonists Stress Disorders Post-Traumatic 03 medical and health sciences Injury Severity Score 0302 clinical medicine medicine Humans Depression (differential diagnoses) Aged Retrospective Studies Depression business.industry Retrospective cohort study Middle Aged Vascular surgery 030227 psychiatry Surgery Blockade Cardiac surgery Cardiothoracic surgery Anesthesia Female business 030217 neurology & neurosurgery Abdominal surgery |
| Zdroj: | World Journal of Surgery |
| ISSN: | 1432-2323 0364-2313 |
| Popis: | Background Approximately half of trauma patients develop post-traumatic depression. It is suggested that beta-blockade impairs trauma memory recollection, reducing depressive symptoms. This study investigates the effect of early beta-blockade on depression following severe traumatic injuries in patients without significant brain injury. Methods Patients were identified by retrospectively reviewing the trauma registry at an urban university hospital between 2007 and 2011. Severe extracranial injuries were defined as extracranial injuries with Abbreviated Injury Scale score ≥3, intracranial Abbreviated Injury Scale score |
| Databáze: | OpenAIRE |
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