Translating solution to solid phase glycosylation conditions

Autor:	Yasmeen Bakhatan, Dror Ben Abba Amiel, Yonatan Sukhran, Chieh-Kai Chan, Wei-Chih Lo, Po-Wei Lu, Pin-Hsuan Liao, Cheng-Chung Wang, Mattan Hurevich
Rok vydání:	2022
Předmět:	Glycosylation Polysaccharides Materials Chemistry Metals and Alloys Ceramics and Composites General Chemistry Catalysis Surfaces Coatings and Films Electronic Optical and Magnetic Materials
Zdroj:	Chemical Communications. 58:11256-11259
ISSN:	1364-548X 1359-7345
DOI:	10.1039/d2cc03831e
Popis:	Optimization of glycosylation conditions for automated glycan assembly is highly challenging, demands wasteful use of precious building blocks, and relies on nontrivial analyses. We developed a semi-quantitative method for automated optimization of glycosylation temperature that utilized minute quantities of donors and translated those conditions to solid-phase glycan assembly.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6bc9c6ae6cc6c8511f2499f576e719b6 https://doi.org/10.1039/d2cc03831e Zobrazit plný text záznamu