Maintaining Muscle Function Across the Lifespan
| Autor: | Carlos J Padilla Colón, W. David Arnold |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
Gerontology
Aging Sarcopenia 030506 rehabilitation Psychological intervention Physical Therapy Sports Therapy and Rehabilitation Physical function Muscle mass Article 03 medical and health sciences 0302 clinical medicine Humans Medicine Muscle Strength Geriatric Assessment Screening procedures Aged business.industry Rehabilitation Physical and Rehabilitation Medicine musculoskeletal system medicine.disease body regions Increased risk Current management Therapeutic exercise 0305 other medical science business human activities 030217 neurology & neurosurgery |
| Zdroj: | Am J Phys Med Rehabil |
| ISSN: | 1537-7385 0894-9115 |
| DOI: | 10.1097/phm.0000000000001429 |
| Popis: | Sarcopenia is a geriatric syndrome currently defined as pathological loss of muscle mass and function. Sarcopenia is not only a major contributor to loss of physical function in older adults but is also associated with increased risk of morbidity, mortality, and increased healthcare costs. As a complex and multifactorial syndrome, sarcopenia has been associated with numerous degenerative changes during the aging process, but there is building evidence for significant contributions to the development of sarcopenia from neurodegenerative changes in the peripheral nervous system. A variety of interventions have been investigated for the treatment of sarcopenia, but current management is primarily focused on nutrition and therapeutic exercise interventions. Great strides have been made to improve screening procedures and diagnostic criteria for sarcopenia, but continued optimization of diagnostic and screening strategies is needed to better identify individuals with sarcopenia or at risk of developing sarcopenia. Understanding and addressing the major drivers of sarcopenia pathogenesis will help develop therapeutics that can reduce the impact of sarcopenia on affected individuals and society. |
| Databáze: | OpenAIRE |
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