Improving the Antimicrobial Performance of Amphiphilic Cationic Antimicrobial Peptides Using Glutamic Acid Full-Scan and Positive Charge Compensation Strategies

Autor:	Xu Ouyang, Beibei Li, Yinyin Yang, Zufang Ba, Jingying Zhang, Tianyue Zhang, Linlin Chang, Fangyan Zhang, Yun Zhang, Hui Liu, Sanhu Gou, Jingman Ni
Rok vydání:	2022
Předmět:	Mice Bacteria Lysine Drug Discovery Molecular Medicine Animals Glutamic Acid Microbial Sensitivity Tests Antimicrobial Peptides Adenosine Monophosphate Anti-Bacterial Agents
Zdroj:	Journal of medicinal chemistry. 65(20)
ISSN:	1520-4804
Popis:	Nonselective toxicity of antimicrobial peptides (AMPs) needs to be solved urgently for their application. Temporin-PE (T-PE, FLPIVAKLLSGLL-NH
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6bc8cca6f08f16e8a465b4b03422f931 https://pubmed.ncbi.nlm.nih.gov/36148510 Zobrazit plný text záznamu