Immunogenicity of the whole antigen and glycoprotein I of varicella-zoster virus (VZV) and the VZV skin test antigen
| Autor: | Kihei Terada, Shoji Kawano, Tetsuro Morita, Yumiko Hiraga |
|---|---|
| Rok vydání: | 1996 |
| Předmět: |
Adult
Male Herpesvirus 3 Human Cellular immunity viruses Stimulation Lymphocyte Activation medicine.disease_cause Virus Immune system Viral Envelope Proteins Antigen medicine Humans Antigens Viral Skin Tests integumentary system business.industry Immunogenicity Varicella zoster virus virus diseases biochemical phenomena metabolism and nutrition Virology Macrophage-1 antigen Pediatrics Perinatology and Child Health Immunology Female business |
| Zdroj: | Pediatrics International. 38:121-123 |
| ISSN: | 1328-8067 |
| Popis: | Specific cellular immunity against the whole antigen and glycoprotein I (gp I) of varicella-zoster virus (VZV) and the skin test antigen were determined for 13 healthy immune adults to compare the immunogenicity of these antigens using a lymphoproliferative assay. The stimulation index values (mean +/- s.d.) were 16.4 +/- 11.2 against the whole VZV antigen, 4.2 +/- 2.9 against the VZV skin test antigen and 1.1 +/- 0.5 against gp I. The immunogenicity of the skin test antigen, which mainly contains gp III and gp IV, appears to be more favorable than that of gp I alone, but to be weaker than that of the whole VZV antigen. |
| Databáze: | OpenAIRE |
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