Tuberculoid leprosy and HLA in Japanese
| Autor: | Hirao Maeda, Tared Juji, Seiji Nakajima, Shigenobu Kobayashi, Kazuo Miyanaga |
|---|---|
| Rok vydání: | 1981 |
| Předmět: |
Adult
musculoskeletal diseases Immunology Mycobacterium Infections Nontuberculous chemical and pharmacologic phenomena Tuberculoid leprosy Human leukocyte antigen Biochemistry Gene Frequency Japan Antigen HLA Antigens Leprosy Genetics medicine Humans Immunology and Allergy Aged Mycobacterium Infections business.industry Histocompatibility Testing Histocompatibility Antigens Class II General Medicine Middle Aged bacterial infections and mycoses medicine.disease Phenotype business Statistical evidence |
| Zdroj: | Tissue Antigens. 18:331-334 |
| ISSN: | 1399-0039 0001-2815 |
| DOI: | 10.1111/j.1399-0039.1981.tb01400.x |
| Popis: | HLA phenotypes of 54 patients with tuberculoid leprosy were compared with those of 167 healthy controls. Frequencies of HLA-A, -B and -C antigens did not differ significantly between the leprosy patients and the controls. However, an increase in the frequencies of DR1, DR2, DRW8 and MT1 antigens and a decrease in the frequencies of DR4 and MT3 antigens were observed in the leprosy patients. Statistical evidence was presented that MT1 antigens were primarily associated with tuberculoid leprosy in Japanese patients rather than DR2. |
| Databáze: | OpenAIRE |
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