Biochemical serum profiles in dogs experimentally infected with Angiostrongylus vasorum (Baillet, 1866)
| Autor: | Marcos Pezzi Guimarães, Márcia Cristina Cury, K. Murta, T.R. Couto, M.C.M. Caldeira, J.M.B. Baptista, Maria das Graças Carvalho, Walter dos Santos Lima |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2004 |
| Předmět: |
Pathology
medicine.medical_specialty Angiostrongylus vasorum Infective larvae digestive system Article Biochemical profile Andrology chemistry.chemical_compound Dogs Creatine kinase (CK-MB) medicine Parasite hosting Animals Creatine Kinase MB Form Urea Aspartate Aminotransferases Dog Diseases Angiostrongylus Creatine Kinase Strongylida Infections Alanine Creatinine General Veterinary biology Alanine Transaminase Globulins General Medicine Blood Proteins gamma-Glutamyltransferase biology.organism_classification Alkaline Phosphatase digestive system diseases Isoenzymes chemistry biology.protein Alkaline phosphatase Parasitology Creatine kinase |
| Zdroj: | Veterinary Parasitology |
| ISSN: | 1873-2550 0304-4017 |
| Popis: | The biochemical profiles of crossbred dogs experimentally infected with the parasite Angiostrongylus vasorum were studied. Two groups of five dogs were experimentally inoculated with 50 and 100 third stage infective larvae (L3) of A. vasorum per kilogram of body weight. A third group of five uninfected animals were used as control. Serum from these animals were used for biochemical tests to measure total and fractioned proteins, urea, creatinine and to determine the activities of aspartate (AST), alanine (ALT) aminotransferase, gamma-glutamyl transferase (GGT), alkaline phosphatase (PAL) and creatine kinase isoenzyme MB (CK-MB). The alpha-1, alpha-2 and beta-globulins fractions showed alterations during acute phase of the infection. No modifications were observed in the biochemical profiles of ALT, AST, GGT, PAL, urea and creatinine. CK-MB was shown to be a good early indicator of cardiac injury in dogs experimentally infected with A. vasorum. |
| Databáze: | OpenAIRE |
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