Effect of intradialytic exercise on bone profile in hemodialysis patients

Autor: Dina A. Farrag, Howaida Abdelhameed Elshinnawy, Ahmed Mohamed Bakr Bakr Mohamed, Moustafa Abd Elnassier AbdElgawad
Rok vydání: 2021
Předmět:
Zdroj: Egyptian Rheumatology and Rehabilitation, Vol 48, Iss 1, Pp 1-7 (2021)
ISSN: 2090-3235
1110-161X
DOI: 10.1186/s43166-021-00071-4
Popis: Background Chronic kidney disease increases the risk of fractures and altered bone and mineral metabolism. Exercise training could be a non-pharmacological therapeutic intervention. The aim of this work is to evaluate the effect of intradialytic exercise training on bone markers in hemodialysis (HD) patients. Results Forty adult patients on regular HD participated in the study. Twenty of which completed 3 months supervised intradialytic cycling exercise program and 20 served as controls. At baseline, there was no difference between both groups regarding age, sex, physical performance, and laboratory studies performed. After 3 months, the exercise group showed significant improvement in short performance battery test (SPBT) total score (PP=0.01) and increase in serum alkaline phosphatase (ALP) and bone specific alkaline phosphatase (BALP) (PPr=0.432, P=0.01 and r=0.645, Pr=−0.503, P=0.01). Conclusion Intradialytic cycling exercise program resulted in significant increase in physical performance associated with decrease in serum PTH and increase in BALP and ALP in HD patients. This indicates the positive influence of exercise not only on physical performance in dialysis patients but also on bone metabolism.
Databáze: OpenAIRE
Externí odkaz: