Pathogenesis of Postmyelographic Arachnoiditis
| Autor: | Victor M. Haughton, John C. Garancis |
|---|---|
| Rok vydání: | 1985 |
| Předmět: |
congenital
hereditary and neonatal diseases and abnormalities Pathology medicine.medical_specialty Time Factors Contrast Media Pathogenesis chemistry.chemical_compound Meglumine Fibrosis Metrizamide medicine Fluorescence microscope Animals Sorbitol Radiology Nuclear Medicine and imaging Myelography medicine.diagnostic_test Chemistry General Medicine medicine.disease Iothalamic Acid nervous system diseases body regions Microscopy Electron Contrast medium Arachnoiditis Microscopy Fluorescence Microscopy Electron Scanning Macaca Arachnoid medicine.drug |
| Zdroj: | Investigative Radiology. 20:85-89 |
| ISSN: | 0020-9996 |
| DOI: | 10.1097/00004424-198501000-00021 |
| Popis: | The causal relationship between a myelogram with an aqueous contrast medium and postmyelographic arachnoiditis has not been clarified. Primates after myelography with metrizamide or meglumine iocarmate were studied with fluorescent microscopy, energy dispersion analysis and with scanning and transmission electron and light microscopy. All controls and, up to the eighth day after myelography, all treated animals had normal-appearing arachnoid membranes by microscopy. After eight days the treated animals had progressively more severe arachnoid fibrosis. Energy dispersive analysis revealed iodine in the arachnoid only up to 24 hours after myelography. Fluorescent microscopy revealed no evidence of immune complexes in the arachnoid. The chronic effects of water-soluble media on the arachnoid are not apparently mediated by contrast medium persisting in the arachnoid or by immune complexes. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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