The Use of a Novel Quantitative Marker of Echogenicity of Pleural Fluid in Parapneumonic Pleural Effusions
Autor: | Alexandros Kalkanis, Foteini Malli, Konstantinos I. Gourgoulianis, Charalampos Varsamas |
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Rok vydání: | 2020 |
Předmět: |
Adult
Male Pulmonary and Respiratory Medicine medicine.medical_specialty Article Subject Demographics Neutrophils Thoracentesis medicine.medical_treatment Gastroenterology Diseases of the respiratory system Internal medicine medicine Humans In patient Clinical care Aged Ultrasonography Aged 80 and over Inflammation Duration of Therapy L-Lactate Dehydrogenase RC705-779 business.industry Echogenicity Exudates and Transudates Pneumonia Hydrogen-Ion Concentration Length of Stay Middle Aged Thoracic ultrasound Pleural Effusion Chest tube placement Glucose Chest Tubes Pleural fluid Female business Research Article |
Zdroj: | Canadian Respiratory Journal, Vol 2020 (2020) Canadian Respiratory Journal |
ISSN: | 1916-7245 1198-2241 |
Popis: | Background. Thoracic ultrasound is an essential tool in the daily clinical care of pleural effusions and especially parapneumonic pleural effusions (PPEs), in terms of diagnosis, management, and follow-up. Hypoechogenicity index (HI) is a quantitative marker of pleural fluid echogenicity. We aimed to examine associations of HI with pleural inflammation in patients with PPE. Methods. All patients included underwent a thoracic ultrasound with HI determination at the first day of their admission for a PPE. Thoracentesis was performed in all patients. Demographics, laboratory measurements, and clinical data were collected prospectively and recorded in all subjects. Results. Twenty-four patients with PPE were included in the study. HI was statistically significantly correlated with intensity of inflammation as suggested by pleural fluid LDH ( p < 0.001 , r = −0.831), pleural fluid glucose ( p = 0.022 , r = 0.474), and pleural fluid pH ( p < 0.001 , r = 0.811). HI was correlated with ADA levels ( p = 0.005 , r = −0.552). We observed a statistically significant correlation of HI with pleural fluid total cell number ( p < 0.001 , r = −0.657) and polymorphonuclears percentage ( p = 0.02 , r = −0.590), as well as days to afebrile ( p = 0.046 , r = −0.411), duration of chest tube placement ( p < 0.001 , r = −0.806), and days of hospitalization ( p = 0.013 , r = −0.501). Discussion. HI presents a fast, easily applicable, objective, and quantitative marker of pleural inflammation that reliably reflects the intensity of pleural inflammation and could potentially guide therapeutic management of PPE. |
Databáze: | OpenAIRE |
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