Palladium nanoparticles synthesized by laser ablation in liquids for antimicrobial applications
| Autor: | Mónica Fernández-Arias, Ana M. Vilas, Mohamed Boutinguiza, Daniel Rodríguez, Felipe Arias-González, Pablo Pou-Álvarez, Antonio Riveiro, Javier Gil, Juan Pou |
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| Přispěvatelé: | Universitat Politècnica de Catalunya. Departament de Ciència i Enginyeria de Materials, Universitat Politècnica de Catalunya. BBT - Biomaterials, Biomecànica i Enginyeria de Teixits, Universidade de Vigo, Instituto de Investigación Sanitaria Galicia Sur, Universitat Internacional de Catalunya |
| Jazyk: | angličtina |
| Rok vydání: | 2022 |
| Předmět: |
2209.10 láseres
Nanopartículas de paladio Caracterización fisicoquímica Nanopartícules General Chemical Engineering 3310 Tecnología Industrial Ablación laser 616.3 Enginyeria biomèdica::Biomaterials [Àrees temàtiques de la UPC] Nanopartícules de pal·ladi Caracterització fisicoquímica Bactericidal activity Cytocompatibility Palladium nanoparticles Bactericida activitat Laser ablation Bactericida actividad 2302 Bioquímica Nanoparticles General Materials Science Physicochemical characterization palladium nanoparticles laser ablation physicochemical characterization bactericidal activity cytocompatibility Citocompatibilitat Citocompatibilidad Ablació làser |
| Zdroj: | Nanomaterials; Volume 12; Issue 15; Pages: 2621 |
| Popis: | Antibiotic resistance is a leading cause of death worldwide. In this paper, we explore new alternatives in the treatment of infections. Noble metal nanoparticles could help to mitigate this problem. In this work, palladium nanoparticles were synthesized by laser ablation in order to explore their antimicrobial capacity. To obtain palladium nanoparticles, a palladium plate immersed in water, or methanol, was ablated, using two pulsed lasers that emit radiation with wavelengths of 532 nm and 1064 nm, respectively. Pure Pd-NPs with crystalline microstructure and rounded shape were obtained. The nanoparticles’ size is more homogeneous if the laser wavelength is 532 nm, and it decreases when methanol is used as solvent, reaching mean diameters smaller than 6 nm. With the objective of studying antimicrobial activity against Staphylococcus aureus, the Pd-NPs were immobilized on the surface of titanium discs. The release of palladium ions was recorded during the first seven days, and the cytotoxicity of the immobilized NPs was also tested with L929 mouse fibroblast cell line. Palladium nanoparticles synthesized by means of the infrared laser in methanol showed a strong inhibitory effect on S. aureus and good cytocompatibility, with no toxic effect on fibroblast cells. Xunta de Galicia | Ref. ED431C 2019/23 Universidad de Vigo | Ref. Beca Margarita Salas Ministerio de Ciencia e Innovación | Ref. PID2020-117900RB-I00 Ministerio de Ciencia e Innovación | Ref. EQC2018-004315-P Ministerio de Educación, Cultura y Deporte | Ref. FPU16/05492 Ministerio de Ciencia, Innovación y Universidades | Ref. RED2018-102803- T |
| Databáze: | OpenAIRE |
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