Prognostic Factors for Neurologic Outcome after Endovascular Revascularization of Acute Symptomatic Occlusion of the Internal Carotid Artery
| Autor: | C. Ahn, K. S. Lim, K. D. Hahm, Choong-Gon Choi, J. G. Leem, Dae Chu Suh, J. S. Kim, Sang Joon Kim, Sun Uck Kwon, Hae Wook Pyun, June-Sung Kim, Dong Hyun Yang, Jung-Bok Lee |
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| Rok vydání: | 2007 |
| Předmět: |
Male
medicine.medical_specialty Endovascular revascularization medicine.medical_treatment Revascularization Logistic regression Modified Rankin Scale medicine.artery Occlusion medicine Humans Carotid Stenosis Radiology Nuclear Medicine and imaging Aged Retrospective Studies Interventional Cerebral Revascularization business.industry Cerebral infarction Thrombolysis Prognosis medicine.disease Surgery Stroke Treatment Outcome Female Neurology (clinical) Internal carotid artery business |
| Zdroj: | AJNR Am J Neuroradiol |
| ISSN: | 1936-959X 0195-6108 |
| DOI: | 10.3174/ajnr.a0492 |
| Popis: | BACKGROUND AND PURPOSE: Management of acute symptomatic internal carotid artery (ICA) occlusion remains controversial. We evaluated outcome predictors of a good recovery in patients with acute symptomatic ICA occlusion. MATERIALS AND METHODS: We retrospectively evaluated 33 consecutive patients (men/women, 23/10; mean age, 66 years) with: 1) acute symptomatic ICA occlusion within 6 hours of symptom onset or with mismatch of symptoms and an early infarct area, 2) National Institutes of Health Stroke Scale (NIHSS) score of 6 or more, and 3) attempted endovascular revascularization of the occluded ICA. Various single and multiple variable analyses were conducted to assess the association of 14 predictors with short-term (1-month NIHSS) and long-term (1-year modified Rankin Scale [mRS]) outcomes. RESULTS: Successful recanalization (at or more than grade 2 distal residual occlusion) was obtained in 14 (42%) of 33 and good recovery (mRS ≤2) after 1 year in 11 (33%) of 33. Distal residual occlusion (DRO; P = .005), initial NIHSS score ( P = .023), and postprocedural thrombolysis in cerebral infarction ( P = .027), retrograde ICA filling ( P = .036), and ophthalmic collaterals ( P = .046) were significant predictors of short-term outcome. DRO ( P = .018) and initial NIHSS ( P = .033) were significant predictors of long-term outcome on univariable analysis. DRO was the only significant predictor for short-term ( P = .026) and long-term outcome ( P = .033) on multivariable logistic regression. CONCLUSIONS: Active revascularization of acute symptomatic ICA occlusion resulted in good recovery in one third of patients after 1 year. DRO is an independent predictor of a favorable clinical outcome. |
| Databáze: | OpenAIRE |
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