Economic and Health Care Burdens of Hepatitis Delta: A Study of Commercially Insured Adults in the United States
| Autor: | Tina John, Carolyn Catalano, Mohamed I. Elsaid, You Li, Navaneeth Narayanan, Vinod K. Rustgi |
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| Rok vydání: | 2019 |
| Předmět: |
0301 basic medicine
Adult Male medicine.medical_specialty Cirrhosis Adolescent viruses Hepatitis C virus MEDLINE medicine.disease_cause Rate ratio 03 medical and health sciences Young Adult 0302 clinical medicine Hepatitis B Chronic Internal medicine Health care medicine Humans Insurance Health Hepatology business.industry virus diseases Health Care Costs Middle Aged medicine.disease Confidence interval Hepatitis D United States Substance abuse 030104 developmental biology Case-Control Studies Propensity score matching 030211 gastroenterology & hepatology Female business |
| Zdroj: | Hepatology (Baltimore, Md.)References. 72(2) |
| ISSN: | 1527-3350 |
| Popis: | BACKGROUND AND AIMS The paucity of data regarding the extent of hepatitis delta virus (HDV) associated health care burden in the United States is an important obstacle to assessing the cost-effectiveness of potential intervention strategies. In this study, we characterized the health care use and cost burdens of HDV in the United States using real-world claims data. APPROACH AND RESULTS We conducted a case-control study using the Truven Health MarketScan Commercial Claims databases from 2011-2014. A total of 2,727 HDV cases were matched 1:1 by sociodemographic characteristics and comorbidities to chronic hepatitis B virus (HBV) controls using propensity scores. The HDV group had significantly higher prevalence of substance abuse, sexually transmitted diseases, decompensated cirrhosis, cirrhosis, and hepatitis C virus compared to patients with chronic HBV. First HDV diagnosis was associated with significant increases in the total number of health care claims (25.61 vs. 28.99; P |
| Databáze: | OpenAIRE |
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