Myopericarditis, as the first sign of rheumatoid arthritis relapse, evaluated by cardiac magnetic resonance
| Autor: | Sophie Mavrogeni, Eliza Sfendouraki, Genovefa Kolovou, Konstantinos Bratis, Evangelia Papadopoulou |
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| Rok vydání: | 2013 |
| Předmět: |
Male
medicine.medical_specialty Myocarditis Immunology Disease Arthritis Rheumatoid Pericarditis Recurrence Internal medicine medicine Immunology and Allergy Humans cardiovascular diseases Prospective Studies Radionuclide Imaging Aged Pharmacology Ejection fraction business.industry Myocardium Heart General Medicine Middle Aged medicine.disease Magnetic Resonance Imaging Pathophysiology Coronary arteries medicine.anatomical_structure Rheumatoid arthritis cardiovascular system Cardiology Disease Progression Female business Myopericarditis Follow-Up Studies |
| Zdroj: | Inflammationallergy drug targets. 12(3) |
| ISSN: | 2212-4055 |
| Popis: | Introduction: Rheumatoid arthritis (RA) affects many organs, including the heart. Cardiac magnetic resonance (CMR) can assess heart pathophysiology in RA. Aim: To evaluate, using CMR, RA patients under remission with recent onset of cardiac symptoms. Patients and Methods: Twenty RA under remission (15F/5M), aged 60±5 yrs, with recent onset of cardiac symptoms (RAH), were prospectively evaluated by CMR. The CMR included left ventricular ejection fraction (LVEF), T2-weighted (T2-W), early (EGE) and late gadolinium enhanced (LGE) images evaluation. Their results were compared with those of 20 RA under remission without cardiac symptoms (RAC) and 18 with systemic lupus erythematosus (SLE) with clinically overt myocarditis. Results: Cardiac enzymes were abnormal in 5/20 RAH. CMR revealed inferior wall myocardial infarction in 2/20 (1M, 1F) and myocarditis in 13/20 (8M/5F) RAH. The T2 ratio of myocardium to skeletal muscle was increased in RAH and SLE compared to RAC (2.5 ± 0.05 and 3.4±0.7 vs 1.8 ± 0.5, p |
| Databáze: | OpenAIRE |
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